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pentobarbital will minimize the extent or impact of vinorelbine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.pentobarbital will minimize the level or impact of midostaurin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Powerful CYP3A4 inducers may possib